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Throughout its history, the NYSDOH AI has been a leader in recommending biomedical interventions to prevent HIV infection, beginning with establishing a standard of care for the prevention of mother-to-child HIV transmission using antiretroviral agents during pregnancy, labor and delivery, and as prophylaxis for the newborn.

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These drugs were among the first to be developed and include zidovudine or azidodeoxythymidine (Retrovir or AZT), lamivudine (Epivir), didanosine (Videx), abacavir (Ziagen), stavudine (Zerit), and zalcitabine (Hivid).

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HBV-coinfected adolescents who require treatment of both infections and who can receive adult doses, tenofovir in combination with an anti-HBV nucleoside (either lamivudine or emtricitabine) can be considered for treatment ( BIII); a combined formulation of emtricitabine and tenofovir (Truvada) is available for adults.

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